265 research outputs found

    Mass Density of Individual Cobalt Nanowires

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    The mass density of nanowires is determined using in-situ resonance frequency experiments combined with quasi-static nanotensile tests. Our results reveal a mass density of 7.36 g/cm3 on average which is below the theoretical density of bulk cobalt. Also the density of electrodeposited cobalt nanowires is found to decrease with the aspect ratio. The results are discussed in terms of the measurement accuracy and the microstructure of the nanowires.Comment: 3 Figure

    Application of Acoustic Sensing Technology for Improving Building Energy Efficiency

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    AbstractBuildings are one of the leading energy consumers in Europe. To improve energy efficiency in the built environment means to optimise the operation of building systems. Acoustics potentially provide an important information source to support the assessment of the operation of buildings. Recently, different approaches to the application of acoustic sensing technology have been studied. This paper presents an overview of three on-going projects which look at how sounds can be utilized to reduce energy consumption in buildings. In the “Sounds for Energy Control of Buildings” (S4ECoB) project the primary goal is the establishment of more energy-efficient buildings through the optimization of existing BMS. The “Experimenting Acoustics in Real environment using Innovative Test-beds” (EAR-IT) project aims to develop acoustic mass flows maps which provide awareness of the flows of masses. The “Energy efficient & Cost competitive retrofitting solutions for Shopping buildings” (EcoShopping) project purpose is to increase the energy efficiency of a building and to optimize the investments necessary in building retrofitting. Diverse methodologies and technologies (wired, wireless and mobile) are tested in realistic conditions provided by each demonstrator

    Towards an interoperability certification method for semantic federated experimental IoT testbeds

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    IoT deployments and then related experiments tend to be highly heterogeneous leading to fragmented and non-interoperable silo solutions. Yet there is a growing need to interconnect such experiments to create rich infrastructures that will underpin the next generation of cross sector IoT applications in particular as using massive number of data. While research have been carried out for IoT test beds and interoperability for some infrastructures less has been done on the data. In this paper, we present the first step of the FIESTA certification method for federated semantic IoT test bed, which provides stakeholders with the means of assessing the interoperability of a given IoT testbed and how it can be federated with other ones to create large facility for experimenter. Focus is given on data and semantic context of the test beds and how they can interoperate together for larger experiments with data

    Erlen : Une interface tangible pour la réduction de la consommation énergétique sur le poste de travail

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    International audienceIn this demonstration paper, we present the Erlen environment. A set of tangible interfaces dedicated to raising awareness of employees and the workplace’s energy consumption reduction.Dans cette article de démonstration, nous présentons l’environne- ment Erlen. Un ensemble d’interfaces tangibles dédiées à la prise de conscience des employés et à la réduction de la consommation énergétique d’un poste de travail

    Erlen : Une interface tangible pour la réduction de la consommation énergétique sur le poste de travail

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    International audienceIn this demonstration paper, we present the Erlen environment. A set of tangible interfaces dedicated to raising awareness of employees and the workplace’s energy consumption reduction.Dans cette article de démonstration, nous présentons l’environne- ment Erlen. Un ensemble d’interfaces tangibles dédiées à la prise de conscience des employés et à la réduction de la consommation énergétique d’un poste de travail

    FormulaciĂłn de estrategias para competitividad ganadera en el contexto de la revoluciĂłn industrial 4.0 : estudio de caso Villa del Rosario

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    La ganadería de doble propósito que se practica en Colombia presenta dificultades en la productividad debido a la poca inversión estatal y a la escasa implementación de tecnologías de punta que ayuden a dejar atrås la explotación artesanal en los hatos ganaderos. En aras a ayudar en estas dificultades se efectuó estå investigación, en donde se desarrollaron estrategias utilizando tecnologías de la revolución industrial 4.0 las cuales ayudan a aumentar la competitividad de un negocio ganadero. El éxito de este trabajo parte de mostrarle al ganadero como es que se descubre la estructura de su negocio y en qué actividades se puede implementar tecnologías de la industria 4.0. que maximicen la competitividad de su negocio. Este trabajo puede ser utilizado como un manual para implementar tecnologías de la industria 4.0 en una finca ganadera, que involucra las variables, actividades, modelos y tecnologías que deberían estar presentes para desarrollar competitivamente un negocio ganadero.The double purpose livestock that is practiced in Colombia presents difficulties in productivity due to the limited state investment and the insufficient implementation of advanced technologies that help to leave behind the traditional exploitation in the livestock farms. to address these difficulties, this research developed strategies using technologies of the industrial revolution 4.0. industrial revolution helped to increase the competitiveness of a livestock business. The success of this research is in showing the farmer how to discover the structure of his business and in which activities he can implement technologies of the 4.0 industry to maximize the competitiveness of his business. This research can be used by farmers to implement 4.0 industry technologies in a livestock farming, which includes the variables, activities, models and technologies that should be present to develop a competitive livestock business.Magíster en Administración MBAMaestrí

    Incidence, risk factors, and CT characteristics of radiation recall pneumonitis induced by immune checkpoint inhibitor in lung cancer.

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    BACKGROUND AND PURPOSE: Radiation recall pneumonitis (RRP) is a delayed radiation-induced lung toxicity triggered by systemic agents, typically anticancer drugs. Immune checkpoint inhibitors (ICIs) have recently been identified as potential causal agents of RRP but its real incidence and potential risk factors remain unknown. MATERIALS AND METHODS: Medical records and CTs of patients treated with programmed death 1 (PD-1) or programmed death ligand 1 (PD-L1) inhibitors for advanced lung cancer between 2014 and 2019 at our tertiary center, and who had a previous history of lung irradiation were retrospectively analyzed. We identified RRP as lung CT modifications occurring in the irradiation field >6 months after conventionally fractionated radiotherapy completion and >1 year after stereotactic body radiation therapy. Clinical and dosimetric data were analyzed to identify potential risk factors for RRP. RESULTS: Among 348 patients treated with ICIs, data from 80 eligible patients were analyzed (median age, 69 years [interquartile range, 11]; 45 men). Fifteen patients (18.8%) presented with RRP. Median time between end of radiotherapy and RRP was 450 days (range, 231-1859). No risk factor was significantly associated with RRP. ICI-related pneumonitis was associated with RRP in 33.3% of cases (p = 0.0021), developing either concomitantly or after RRP. Incidence of grade ≄ 3 pneumonitis in the RRP population was 13.3 %. CONCLUSION: We demonstrated a high incidence of RRP (18.8%) in our population of previously irradiated patients treated with ICIs for lung cancer. We identified no risk factors for RRP, but an association was noted between RRP and ICI-related pneumonitis.Peer reviewe

    The project ENDORSE: exploiting EO data to develop pre-market services in renewable energy

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    International audienceThe ENDORSE project is co-funded by the FP7 programme of the European Commission, from 2011 to 2013. It exploits the atmosphere service MACC of the European GMES programme (Global Monitoring for Environment and Security) together with other Earth Observation (EO) data and modelling. It aims at providing public authorities and private investors with accurate evaluation and forecasts of renewable resources. The focus is on the devel-opment of downstream services that create added-value information. We present here the achievements of the first period. A very accurate though fast algorithm describing the position of the sun in the sky has been developed. A series of recommendations for quality control of meteorological data have been issued. All algorithms are available as code sources and are being implemented as Web processing services (WPS). Support vector machine techniques prove successful to map the air temperature at 2-m height from satellite images and a few measurements at ground level. The next development of ENDORSE is a portfolio of pre-market downstream services, serving as precursors and examples of best practices for similar services. The resulting services will be described using the INSPIRE metadata and declared in an existing Catalog Service for the Web (CSW) dedicated to energy. Finally, we discuss the mutual benefits between GEOSS (Global Earth Observation System of Systems) and ENDORSE

    Adult Stromal Cells Derived from Human Adipose Tissue Provoke Pancreatic Cancer Cell Death both In Vitro and In Vivo

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    1932-6203 (Electronic) Journal Article Research Support, Non-U.S. Gov'tBACKGROUND: Normal tissue homeostasis is maintained by dynamic interactions between epithelial cells and their microenvironment. Disrupting this homeostasis can induce aberrant cell proliferation, adhesion, function and migration that might promote malignant behavior. Indeed, aberrant stromal-epithelial interactions contribute to pancreatic ductal adenocarcinoma (PDAC) spread and metastasis, and this raises the possibility that novel stroma-targeted therapies represent additional approaches for combating this malignant disease. The aim of the present study was to determine the effect of human stromal cells derived from adipose tissue (ADSC) on pancreatic tumor cell proliferation. PRINCIPAL FINDINGS: Co-culturing pancreatic tumor cells with ADSC and ADSC-conditioned medium sampled from different donors inhibited cancer cell viability and proliferation. ADSC-mediated inhibitory effect was further extended to other epithelial cancer-derived cell lines (liver, colon, prostate). ADSC conditioned medium induced cancer cell necrosis following G1-phase arrest, without evidence of apoptosis. In vivo, a single intra-tumoral injection of ADSC in a model of pancreatic adenocarcinoma induced a strong and long-lasting inhibition of tumor growth. CONCLUSION: These data indicate that ADSC strongly inhibit PDAC proliferation, both in vitro and in vivo and induce tumor cell death by altering cell cycle progression. Therefore, ADSC may constitute a potential cell-based therapeutic alternative for the treatment of PDAC for which no effective cure is available
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